Hydrogen borrowing-based methods for the construction of quaternary stereocentres

Compounds containing quaternary stereocentres are a valuable motif in biologically active compounds. Herein we present our strategy to utilise the hydrogen borrowing manifold to access α-quaternary ketones via a tandem acceptorless dehydrogenation-cyclisation cascade. This new application of the met...

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Bibliographic Details
Main Authors: Crompton, J, Jenkins, T, Rowe, S, Donohoe, T
Format: Journal article
Language:English
Published: Wiley 2025