Hydrogen borrowing-based methods for the construction of quaternary stereocentres

Compounds containing quaternary stereocentres are a valuable motif in biologically active compounds. Herein we present our strategy to utilise the hydrogen borrowing manifold to access α-quaternary ketones via a tandem acceptorless dehydrogenation-cyclisation cascade. This new application of the met...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Crompton, J, Jenkins, T, Rowe, S, Donohoe, T
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: Wiley 2025