Effects of internal chloride on ATP-sensitive K-channels in mouse pancreatic beta-cells.
The effect of internal Cl- on the K-ATP channel of pancreatic beta-cells was examined. Reducing Cl- from 140mM to 14mM potentiated channel activity (NPO) approximately 4.5 fold in 60% of patches but was without effect in 40% of patches. The Ki for channel inhibition by ATP was not changed. The inhib...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1994
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