Do antiviral CD8+ T cells select hepatitis C virus escape mutants? Analysis in diverse epitopes targeted by human intrahepatic CD8+ T lymphocytes.
Hepatitis C virus (HCV) is a variable RNA virus that can readily establish persistent infection. Cellular immune responses are important in the early control of the virus. Evidence from animal models suggests that mutation in epitopes recognized by CD8+ T lymphocytes may play an important role in th...
Κύριοι συγγραφείς: | Komatsu, H, Lauer, G, Pybus, O, Ouchi, K, Wong, D, Ward, S, Walker, B, Klenerman, P |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2006
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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CD8 epitope escape and reversion in acute HCV infection.
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Effects of neutralizing antibodies on escape from CD8+ T-cell responses in HIV-1 infection.
ανά: Wikramaratna, P, κ.ά.
Έκδοση: (2015)