Structural basis for the interference between nicorandil and sulfonylurea action.

Nicorandil is a new antianginal agent that potentially may be used to treat the cardiovascular side effects of diabetes. It is both a nitric oxide donor and an opener of ATP-sensitive K(+) (K(ATP)) channels in muscle and thereby causes vasodilation of the coronary vasculature. The aim of this study...

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Bibliographic Details
Main Authors: Reimann, F, Ashcroft, F, Gribble, F
Format: Journal article
Language:English
Published: 2001