Effect of castration and castration with hormone replacement on the plasma prolactin responses to neuroendocrine challenge with i.v. mCPP in the male rat following a low tryptophan diet.

Previous studies have shown that castration increased brain 5-HT synthesis and that sex steroid hormone treatment can reverse this effect. Tryptophan (TRP) depletion has been shown to reduce brain 5-HT synthesis and to cause the post-synaptic 5-HT receptors to up-regulate. We have studied the effect...

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Bibliographic Details
Main Authors: Franklin, M, Craven, R, Cowen, P
Format: Journal article
Language:English
Published: 1996