Effect of castration and castration with hormone replacement on the plasma prolactin responses to neuroendocrine challenge with i.v. mCPP in the male rat following a low tryptophan diet.
Previous studies have shown that castration increased brain 5-HT synthesis and that sex steroid hormone treatment can reverse this effect. Tryptophan (TRP) depletion has been shown to reduce brain 5-HT synthesis and to cause the post-synaptic 5-HT receptors to up-regulate. We have studied the effect...
Main Authors: | Franklin, M, Craven, R, Cowen, P |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1996
|
Similar Items
-
THE EFFECTS OF A LOW TRYPTOPHAN DIET ON PLASMA PROLACTIN FOLLOWING NEUROENDOCRINE CHALLENGES WITH MCPP AND D-FENFLURAMINE IN THE RAT
by: Franklin, M, et al.
Published: (1993) -
SSRI treatment decreases prolactin and hyperthermic responses to mCPP.
by: Quested, D, et al.
Published: (1997) -
Effect of a long-term low tryptophan diet on the prolactin responses to the 5-HT1A and 5-HT2C agonists, 8-OH-DPAT and mCPP in the male rat.
by: Franklin, M, et al.
Published: (1999) -
The effects of administration of mCPP on psychological, cognitive, cardiovascular, hormonal and MHPG measurements in human volunteers.
by: Silverstone, P, et al.
Published: (1994) -
The effects of a low tryptophan diet on brain 5 -HT metabolism and 5-HT-mediated neuroendocrine responses in the male rat.
by: Franklin, M, et al.
Published: (1995)