Statistical challenges in the detection of mutation and variation using high throughput sequencing
The aim of this thesis is to obtain a better understanding of mutation rates within as well as between the genomes of humans and chimpanzees using data generated by high throughput sequencers. I will start with a review of the field and an overview of the technologies and protocols used to generate...
Автор: | Pfeifer, S |
---|---|
Інші автори: | McVean, G |
Формат: | Дисертація |
Мова: | English |
Опубліковано: |
2012
|
Предмети: |
Схожі ресурси
-
An integrated genomic approach for the identification and analysis of single nucleotide polymorphisms that affect cancer in humans
за авторством: Repapi, E
Опубліковано: (2013) -
The estimation of recombination rates from population genetic data
за авторством: Auton, A
Опубліковано: (2007) -
Application of the Neutral Indel Model to genome sequences for diverse metazoans
за авторством: Meader, S
Опубліковано: (2010) -
A method for the identification of biological pathways
за авторством: Honti, F
Опубліковано: (2014) -
Statistical HLA type imputation from large and heterogeneous datasets
за авторством: Dilthey, A
Опубліковано: (2012)