Creatine uptake in mouse hearts with genetically altered creatine levels.

Creatine plays an important role in energy metabolism in the heart. Cardiomyocytes accumulate creatine via a specific creatine transporter (CrT), the capacity of which is reduced in the failing heart, resulting in lower myocardial creatine concentration. Therefore, to gain insight into how the CrT i...

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Bibliographic Details
Main Authors: ten Hove, M, Makinen, K, Sebag-Montefiore, L, Hunyor, I, Fischer, A, Wallis, J, Isbrandt, D, Lygate, C, Neubauer, S
Format: Journal article
Language:English
Published: 2008