The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy.

DNA damaging agents such as radiotherapy and gemcitabine are frequently used for the treatment of pancreatic cancer. However, these treatments typically provide only modest benefit. Improving the low survival rate for pancreatic cancer patients therefore remains a major challenge in oncology. Inhibi...

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Bibliographic Details
Main Authors: Prevo, R, Fokas, E, Reaper, P, Charlton, P, Pollard, JR, McKenna, W, Muschel, R, Brunner, T
Format: Journal article
Language:English
Published: 2012