Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase

Cytoplasmic terminal uridylyl transferases comprise a conserved family of enzymes that negatively regulate the stability or biological activity of a variety of eukaryotic RNAs, including mRNAs and tumor-suppressor let-7 microRNAs. Here we describe crystal structures of the Schizosaccharomyces pombe...

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Bibliografiske detaljer
Main Authors: Yates, L, Fleurdépine, S, Rissland, O, De Colibus, L, Harlos, K, Norbury, C, Gilbert, R
Format: Journal article
Sprog:English
Udgivet: 2012