TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens

<p style="text-align:justify;"> <b>Background:</b> Measuring the impact of combinations of genetic or chemical perturbations on cellular fitness, sometimes referred to as synthetic lethal screening, is a powerful method for obtaining novel insights into gene function and...

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Bibliographic Details
Main Authors: Muellner, M, Duernberger, G, Ganglberger, F, Kerzendorfer, C, Uras, I, Schoenegger, A, Bagienski, K, Colinge, J, Nijman, S
Format: Journal article
Language:English
Published: BioMed Central 2014