Chemistry-based functional proteomics: mechanism-based activity-profiling tools for ubiquitin and ubiquitin-like specific proteases.

Determining the biological function of newly discovered gene products requires the development of novel functional approaches. To facilitate this task, recent developments in proteomics include small molecular probes that target proteolytic enzyme families including serine, threonine, and cysteine p...

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Bibliographic Details
Main Authors: Hemelaar, J, Galardy, P, Borodovsky, A, Kessler, B, Ploegh, H, Ovaa, H
Format: Journal article
Language:English
Published: 2004