Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers

<p><strong>Objectives</strong></p> <p>To characterize early childhood social-communication skills and autistic traits in children born very preterm using the Quantitative Checklist for Autism in Toddlers (Q-CHAT) and explore neonatal and sociodemographic factors associa...

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Huvudupphovsmän: Wong, H, Huertas-Ceballos, A, Cowan, F, Modi, N, Medicines for Neonates Investigator Group
Övriga upphovsmän: Petrou, S
Materialtyp: Journal article
Språk:English
Publicerad: Elsevier 2013
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author Wong, H
Huertas-Ceballos, A
Cowan, F
Modi, N
Medicines for Neonates Investigator Group
author2 Petrou, S
author_facet Petrou, S
Wong, H
Huertas-Ceballos, A
Cowan, F
Modi, N
Medicines for Neonates Investigator Group
author_sort Wong, H
collection OXFORD
description <p><strong>Objectives</strong></p> <p>To characterize early childhood social-communication skills and autistic traits in children born very preterm using the Quantitative Checklist for Autism in Toddlers (Q-CHAT) and explore neonatal and sociodemographic factors associated with Q-CHAT scores.</p> <p><strong>Study design</strong></p> <p>Parents of children born before 30 weeks gestation and enrolled in a study evaluating routinely collected neurodevelopmental data between the post-menstrual ages of 20 and 28 months were invited to complete the Q-CHAT questionnaire. Children with severe neurosensory disabilities and cerebral palsy were excluded. Participants received neurodevelopmental assessments using the Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III). Q-CHAT scores of this preterm cohort were compared with published general population scores. The association between Bayley-III cognitive and language scores and neonatal and sociodemographic factors with Q-CHAT scores were examined.</p> <p><strong>Results</strong></p> <p>Q-CHAT questionnaires were completed from 141 participants. At a mean post-menstrual age of 24 months, the Q-CHAT scores of the preterm cohort (mean 33.7, SD 8.3) were significantly higher than published general population scores (mean 26.7; SD 7.8), indicating greater social-communication difficulty and autistic behavior. Preterm children received higher scores, particularly in the categories of restricted, repetitive, stereotyped behavior, communication, and sensory abnormalities. Lower Bayley-III language scores and non-white ethnicity were associated with higher Q-CHAT scores.</p> <p><strong>Conclusions</strong></p> <p>Preterm children display greater social-communication difficulty and autistic behavior than the general population in early childhood as assessed by the Q-CHAT. The implications for longer-term outcome will be important to assess.</p>
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spelling oxford-uuid:e4e6a0db-4f82-4ed1-b9bf-5e621ec28c212022-03-27T10:19:48ZEvaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlersJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e4e6a0db-4f82-4ed1-b9bf-5e621ec28c21EnglishSymplectic Elements at OxfordElsevier2013Wong, HHuertas-Ceballos, ACowan, FModi, NMedicines for Neonates Investigator GroupPetrou, S<p><strong>Objectives</strong></p> <p>To characterize early childhood social-communication skills and autistic traits in children born very preterm using the Quantitative Checklist for Autism in Toddlers (Q-CHAT) and explore neonatal and sociodemographic factors associated with Q-CHAT scores.</p> <p><strong>Study design</strong></p> <p>Parents of children born before 30 weeks gestation and enrolled in a study evaluating routinely collected neurodevelopmental data between the post-menstrual ages of 20 and 28 months were invited to complete the Q-CHAT questionnaire. Children with severe neurosensory disabilities and cerebral palsy were excluded. Participants received neurodevelopmental assessments using the Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III). Q-CHAT scores of this preterm cohort were compared with published general population scores. The association between Bayley-III cognitive and language scores and neonatal and sociodemographic factors with Q-CHAT scores were examined.</p> <p><strong>Results</strong></p> <p>Q-CHAT questionnaires were completed from 141 participants. At a mean post-menstrual age of 24 months, the Q-CHAT scores of the preterm cohort (mean 33.7, SD 8.3) were significantly higher than published general population scores (mean 26.7; SD 7.8), indicating greater social-communication difficulty and autistic behavior. Preterm children received higher scores, particularly in the categories of restricted, repetitive, stereotyped behavior, communication, and sensory abnormalities. Lower Bayley-III language scores and non-white ethnicity were associated with higher Q-CHAT scores.</p> <p><strong>Conclusions</strong></p> <p>Preterm children display greater social-communication difficulty and autistic behavior than the general population in early childhood as assessed by the Q-CHAT. The implications for longer-term outcome will be important to assess.</p>
spellingShingle Wong, H
Huertas-Ceballos, A
Cowan, F
Modi, N
Medicines for Neonates Investigator Group
Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers
title Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers
title_full Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers
title_fullStr Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers
title_full_unstemmed Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers
title_short Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers
title_sort evaluation of early childhood social communication difficulties in children born preterm using the quantitative checklist for autism in toddlers
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