Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers
<p><strong>Objectives</strong></p> <p>To characterize early childhood social-communication skills and autistic traits in children born very preterm using the Quantitative Checklist for Autism in Toddlers (Q-CHAT) and explore neonatal and sociodemographic factors associa...
| Auteurs principaux: | , , , , |
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| Autres auteurs: | |
| Format: | Journal article |
| Langue: | English |
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Elsevier
2013
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| _version_ | 1826301868703219712 |
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| author | Wong, H Huertas-Ceballos, A Cowan, F Modi, N Medicines for Neonates Investigator Group |
| author2 | Petrou, S |
| author_facet | Petrou, S Wong, H Huertas-Ceballos, A Cowan, F Modi, N Medicines for Neonates Investigator Group |
| author_sort | Wong, H |
| collection | OXFORD |
| description | <p><strong>Objectives</strong></p> <p>To characterize early childhood social-communication skills and autistic traits in children born very preterm using the Quantitative Checklist for Autism in Toddlers (Q-CHAT) and explore neonatal and sociodemographic factors associated with Q-CHAT scores.</p> <p><strong>Study design</strong></p> <p>Parents of children born before 30 weeks gestation and enrolled in a study evaluating routinely collected neurodevelopmental data between the post-menstrual ages of 20 and 28 months were invited to complete the Q-CHAT questionnaire. Children with severe neurosensory disabilities and cerebral palsy were excluded. Participants received neurodevelopmental assessments using the Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III). Q-CHAT scores of this preterm cohort were compared with published general population scores. The association between Bayley-III cognitive and language scores and neonatal and sociodemographic factors with Q-CHAT scores were examined.</p> <p><strong>Results</strong></p> <p>Q-CHAT questionnaires were completed from 141 participants. At a mean post-menstrual age of 24 months, the Q-CHAT scores of the preterm cohort (mean 33.7, SD 8.3) were significantly higher than published general population scores (mean 26.7; SD 7.8), indicating greater social-communication difficulty and autistic behavior. Preterm children received higher scores, particularly in the categories of restricted, repetitive, stereotyped behavior, communication, and sensory abnormalities. Lower Bayley-III language scores and non-white ethnicity were associated with higher Q-CHAT scores.</p> <p><strong>Conclusions</strong></p> <p>Preterm children display greater social-communication difficulty and autistic behavior than the general population in early childhood as assessed by the Q-CHAT. The implications for longer-term outcome will be important to assess.</p> |
| first_indexed | 2024-03-07T05:38:54Z |
| format | Journal article |
| id | oxford-uuid:e4e6a0db-4f82-4ed1-b9bf-5e621ec28c21 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:38:54Z |
| publishDate | 2013 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:e4e6a0db-4f82-4ed1-b9bf-5e621ec28c212022-03-27T10:19:48ZEvaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlersJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e4e6a0db-4f82-4ed1-b9bf-5e621ec28c21EnglishSymplectic Elements at OxfordElsevier2013Wong, HHuertas-Ceballos, ACowan, FModi, NMedicines for Neonates Investigator GroupPetrou, S<p><strong>Objectives</strong></p> <p>To characterize early childhood social-communication skills and autistic traits in children born very preterm using the Quantitative Checklist for Autism in Toddlers (Q-CHAT) and explore neonatal and sociodemographic factors associated with Q-CHAT scores.</p> <p><strong>Study design</strong></p> <p>Parents of children born before 30 weeks gestation and enrolled in a study evaluating routinely collected neurodevelopmental data between the post-menstrual ages of 20 and 28 months were invited to complete the Q-CHAT questionnaire. Children with severe neurosensory disabilities and cerebral palsy were excluded. Participants received neurodevelopmental assessments using the Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III). Q-CHAT scores of this preterm cohort were compared with published general population scores. The association between Bayley-III cognitive and language scores and neonatal and sociodemographic factors with Q-CHAT scores were examined.</p> <p><strong>Results</strong></p> <p>Q-CHAT questionnaires were completed from 141 participants. At a mean post-menstrual age of 24 months, the Q-CHAT scores of the preterm cohort (mean 33.7, SD 8.3) were significantly higher than published general population scores (mean 26.7; SD 7.8), indicating greater social-communication difficulty and autistic behavior. Preterm children received higher scores, particularly in the categories of restricted, repetitive, stereotyped behavior, communication, and sensory abnormalities. Lower Bayley-III language scores and non-white ethnicity were associated with higher Q-CHAT scores.</p> <p><strong>Conclusions</strong></p> <p>Preterm children display greater social-communication difficulty and autistic behavior than the general population in early childhood as assessed by the Q-CHAT. The implications for longer-term outcome will be important to assess.</p> |
| spellingShingle | Wong, H Huertas-Ceballos, A Cowan, F Modi, N Medicines for Neonates Investigator Group Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers |
| title | Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers |
| title_full | Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers |
| title_fullStr | Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers |
| title_full_unstemmed | Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers |
| title_short | Evaluation of early childhood social-communication difficulties in children born preterm using the quantitative checklist for autism in toddlers |
| title_sort | evaluation of early childhood social communication difficulties in children born preterm using the quantitative checklist for autism in toddlers |
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