Detection of HIV type 1 gag-specific CD4(+) T cell responses in acutely infected infants.

Multiple HIV-1-specific cytokine and proliferative responses by CD4(+) T cells have not been studied in acutely infected infants. Using an intracellular cytokine staining assay, 34 untreated clade C HIV-1-infected infants (2-102 days old) were assessed for IFN-gamma, 28/34 for IL-2, and 26/34 for TN...

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Main Authors: Ramduth, D, Thobakgale, C, Mkhwanazi, N, De Pierres, C, Reddy, S, van der Stok, M, Mncube, Z, Mphatswe, W, Blanckenberg, N, Cengimbo, A, Prendergast, A, Tudor-Williams, G, Dong, K, Jeena, P, Coovadia, H, Day, C, Kiepiela, P, Goulder, P, Walker, B
Format: Journal article
Language:English
Published: 2008