Huge (14-, 21-, 28-, 35-, 56- and 70-membered ring) macrocyclic lactams - a novel family of carbopeptoid-cyclodextrins
Hydrogenation of linear ω-azido-pentafluorophenyl esters gives cyclic peptides containing 14-, 21-, 28-, 35-, 56- and 70-membered ring lactams from oligomers derived from ε-amino acids in excellent to moderate yields with a lack of racemisation during the cyclisation step. © 2003 Elsevier Ltd. All r...
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Journal article |
| Langue: | English |
| Publié: |
2004
|