An intronic Runx1 enhancer directs transcription to the emerging hematopoietic system of the mouse embryo

An intronic Runx1 enhancer directs transcription to the emerging hematopoietic system of the mouse embryo

Xehetasun bibliografikoak
Egile Nagusiak:	Nottingham, W, Burgess, M, Speck, C, Barton, D, Kong-a-san, J, Li, P, Sloane-Stanley, J, Sharpe, J, De Bruijn, M
Formatua:	Conference item
Argitaratua:	2007

Antzeko izenburuak

Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer.
nork: Nottingham, W, et al.
Argitaratua: (2007)

The mouse Runx1 +23 hematopoietic stem cell enhancer confers hematopoietic specificity to both Runx1 promoters.
nork: Bee, T, et al.
Argitaratua: (2009)

Hematopoietic stem cell emergence in the conceptus and the role of Runx1.
nork: Swiers, G, et al.
Argitaratua: (2010)

Runx1 is expressed in adult mouse hematopoietic stem cells and differentiating myeloid and lymphoid cells, but not in maturing erythroid cells.
nork: North, T, et al.
Argitaratua: (2004)

DISTINCT RUNX1 ENHANCERS DIRECT TRANSCRIPTION TO DISCRETE STAGES OF DEVELOPMENTAL HEMATOPOIESIS
nork: O'Rourke, J, et al.
Argitaratua: (2012)

Isolation and analysis of hematopoietic stem cells from mouse embryos.
nork: Dzierzak, E, et al.
Argitaratua: (2002)

THE RUNX1+23 ENHANCER IS ACTIVE IN CELLS WITH BOTH ENDOTHELIAL AND HEMATOPOIETIC CHARACTERISTICS DURING MOUSE DEVELOPMENTAL HEMATOPOIESIS
nork: Swiers, G, et al.
Argitaratua: (2009)

A RUNX1-SMAD6 RHEOSTAT CONTROLS RUNX1 LEVELS AND REGULATES HEMATOPOIESIS IN THE DEVELOPING EMBRYO
nork: Pimanda, J, et al.
Argitaratua: (2010)

Hematopoietic Cell Autonomous Disruption of Hematopoiesis in a Germline Loss-of-function Mouse Model of RUNX1-FPD
nork: Martijn P. T. Ernst, et al.
Argitaratua: (2023-02-01)

Runx1 loss minimally impacts long-term hematopoietic stem cells.
nork: Xiongwei Cai, et al.
Argitaratua: (2011-01-01)

Alternative Runx1 promoter usage in mouse developmental hematopoiesis.
nork: Bee, T, et al.
Argitaratua: (2009)

Haploinsufficiency of AML1 affects the temporal and spatial generation of hematopoietic stem cells in the mouse embryo.
nork: Cai, Z, et al.
Argitaratua: (2000)

Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development
nork: Owens, DDG, et al.
Argitaratua: (2022)

Using RUNX1 enhancer-reporter transgenic mouse models to dissect discrete stages of developmental hematopoiesis
nork: Rode, C, et al.
Argitaratua: (2014)

Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells
nork: Yoshiki Omatsu, et al.
Argitaratua: (2022-05-01)

Differences in the patterns of transcription factor binding in the human and mouse alpha globin clusters point to potential differences in their regulation.
nork: De Gobbi, M, et al.
Argitaratua: (2005)

The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity.
nork: Pimanda, J, et al.
Argitaratua: (2007)

Molecular characterization of the mouse superior lateral parabrachial nucleus through expression of the transcription factor Runx1.
nork: Chrissandra J Zagami, et al.
Argitaratua: (2010-11-01)

Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver.
nork: Landry, JR, et al.
Argitaratua: (2008)

Identification of a novel long non-coding RNA within RUNX1 intron 5
nork: Nicolás Schnake, et al.
Argitaratua: (2019-07-01)

The dynamics of RUNX1-RUNX1T1 transcript levels after allogeneic hematopoietic stem cell transplantation predict relapse in patients with t(8;21) acute myeloid leukemia
nork: Ya-Zhen Qin, et al.
Argitaratua: (2017-02-01)

Runx transcription factors in neuronal development
nork: Shiga Takashi, et al.
Argitaratua: (2008-08-01)

Nonredundant roles for Runx1 alternative promoters reflect their activity at discrete stages of developmental hematopoiesis.
nork: Bee, T, et al.
Argitaratua: (2010)

Hematopoietic Transcription Factor RUNX1 is Essential for Promoting Macrophage–Myofibroblast Transition in Non‐Small‐Cell Lung Carcinoma
nork: Philip Chiu‐Tsun Tang, et al.
Argitaratua: (2024-01-01)

Wip1 regulates hematopoietic stem cell development in the mouse embryo
nork: Wenyan He, et al.
Argitaratua: (2020-02-01)

RUNX3 interactome reveals novel centrosomal targeting of RUNX family of transcription factors
nork: Chuang, Linda Shyue Huey, et al.
Argitaratua: (2013)

RUNX1 Mutations in Inherited and Sporadic Leukemia
nork: Dana C. Bellissimo, et al.
Argitaratua: (2017-12-01)

RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia
nork: Vasily V. Grinev, et al.
Argitaratua: (2021-01-01)

Expression of the Ly-6A (Sca-1) lacZ transgene in mouse haematopoietic stem cells and embryos.
nork: Ma, X, et al.
Argitaratua: (2002)

From hemangioblast to hematopoietic stem cell: an endothelial connection?
nork: Jaffredo, T, et al.
Argitaratua: (2005)

Detained introns are a novel, widespread class of post-transcriptionally spliced introns
nork: Sharp, Phillip A., et al.
Argitaratua: (2015)

Identification of Introns by Reverse-Transcription PCR
nork: Hannah Alexander, et al.
Argitaratua: (1996-05-01)

Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers
nork: Anuradha Illendula, et al.
Argitaratua: (2016-06-01)

A Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesis.
nork: Knezevic, K, et al.
Argitaratua: (2011)

RUNX3 levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance
nork: Peter Balogh, et al.
Argitaratua: (2020-04-01)

Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies
nork: Margarita Parada-Kusz, et al.
Argitaratua: (2018-11-01)

CSF3R T618I Collaborates With RUNX1-RUNX1T1 to Expand Hematopoietic Progenitors and Sensitizes to GLI Inhibition
nork: Anja S. Swoboda, et al.
Argitaratua: (2023-10-01)

Runx1 promotes proliferation and neuronal differentiation in adult mouse neurosphere cultures
nork: T.T. Logan, et al.
Argitaratua: (2015-11-01)

Genome-wide computational screen for bloon stem cell enhancers integrates RUNX1 and the BMP signaling pathway into the SCL transcriptional network
nork: Pimanda, J, et al.
Argitaratua: (2007)

A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells.
nork: van Riel, B, et al.
Argitaratua: (2012)