Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering.

The inhibitory T-cell surface-expressed receptor, cytotoxic T lymphocyte-associated antigen-4 (CTLA-4), which belongs to the class of cell surface proteins phosphorylated by extrinsic tyrosine kinases that also includes antigen receptors, binds the related ligands, B7-1 and B7-2, expressed on antige...

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Bibliographic Details
Main Authors: Yu, C, Sonnen, A, George, R, Dessailly, B, Stagg, L, Evans, E, Orengo, C, Stuart, D, Ladbury, J, Ikemizu, S, Gilbert, R, Davis, S
Format: Journal article
Language:English
Published: 2011