Review article: the therapeutic potential of 5-HT3 receptor antagonists in the treatment of irritable bowel syndrome.

There is evidence from studies, in both animals and humans, that 5-HT3 receptor blockade has potential value in the treatment of irritable bowel syndrome, particularly in those patients with diarrhoea-predominant bowel habits. New findings suggest that 5-HT3 receptors exist on gut afferent neurones...

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Bibliographic Details
Main Authors: Humphrey, P, Bountra, C, Clayton, N, Kozlowski, K
Format: Journal article
Language:English
Published: Blackwell Publishing Ltd. 1999