Design, synthesis, and functional activity of labeled CD1d glycolipid agonists.

Invariant natural killer T cells (iNKT cells) are restricted by CD1d molecules and activated upon CD1d-mediated presentation of glycolipids to T cell receptors (TCRs) located on the surface of the cell. Because the cytokine response profile is governed by the structure of the glycolipid, we sought a...

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Bibliographic Details
Main Authors: Jervis, P, Polzella, P, Wojno, J, Jukes, J, Ghadbane, H, Garcia Diaz, Y, Besra, G, Cerundolo, V, Cox, L
Format: Journal article
Language:English
Published: 2013