Defining ELISpot cut-offs from unreplicated test and control wells

In the absence of replication of wells, empirical criteria for enzyme-linked immunospot (ELISpot) positivity use fixed differences or ratios between spot forming units (SFU) counts between test and control. We propose an alternative approach which first identifies the optimally variance-stabilizing...

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Bibliographic Details
Main Authors: Alexander, N, Fox, A, Lien, V, Dong, T, Lee, L, Hang, N, Mai, L, Horby, P
Format: Journal article
Language:English
Published: 2013