Site-selective modification of peptides using rhodium and palladium catalysis: complementary electrophilic and nucleophilic arylation.

The site-selective modification of peptides containing dehydroalanine, tyrosine and tryptophan residues has been achieved using rhodium catalysed conjugate additions or palladium catalysed aryl-amination and -etherification reactions.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chapman, C, Matsuno, A, Frost, C, Willis, M
Μορφή: Journal article
Γλώσσα:English
Έκδοση: 2007
Περιγραφή
Περίληψη:The site-selective modification of peptides containing dehydroalanine, tyrosine and tryptophan residues has been achieved using rhodium catalysed conjugate additions or palladium catalysed aryl-amination and -etherification reactions.