Site-selective modification of peptides using rhodium and palladium catalysis: complementary electrophilic and nucleophilic arylation.

The site-selective modification of peptides containing dehydroalanine, tyrosine and tryptophan residues has been achieved using rhodium catalysed conjugate additions or palladium catalysed aryl-amination and -etherification reactions.

Bibliografische gegevens
Hoofdauteurs: Chapman, C, Matsuno, A, Frost, C, Willis, M
Formaat: Journal article
Taal:English
Gepubliceerd in: 2007
Omschrijving
Samenvatting:The site-selective modification of peptides containing dehydroalanine, tyrosine and tryptophan residues has been achieved using rhodium catalysed conjugate additions or palladium catalysed aryl-amination and -etherification reactions.