THE STEREOSPECIFIC SYNTHESIS OF (-)-(8R) AND (-)-(8S)-METHYLCANADINE
Regioselective complexation of the dimethoxy arene ring of canadine to the Cr(CO)2 moiety gives two diastereoisomers which are separated by flash chromatography. Deprotonatlon of either diastereoisomer with n-butyllithium followed by addition of methyl iodide or trimethylsilyl chloride gives C11-met...
| Main Authors: | , , , |
|---|---|
| Formato: | Journal article |
| Idioma: | English |
| Publicado em: |
1988
|