Altered in vitro adaptive responses of lymphocyte Na+,K(+)-ATPase in patients with manic depressive psychosis.
When lymphocytes from healthy subjects are incubated in lithium (8 mM) or ethacrynate (1 microM) they show a time-dependent adaptive response, which consists of a significant increase in the number of Na+,K(+)-ATPase molecules in the lymphocyte membrane. We have studied the lymphocytes from nine eut...
المؤلفون الرئيسيون: | Wood, A, Smith, C, Clarke, E, Cowen, P, Aronson, J, Grahame-Smith, D |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
1991
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مواد مشابهة
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The upregulation of Na+,K(+)-ATPase pump numbers in lymphocytes from the first-degree unaffected relatives of patients with manic depressive psychosis in response to in vitro lithium and sodium ethacrynate.
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