A Bayesian Method for Detecting and Characterizing Allelic Heterogeneity and Boosting Signals in Genome-Wide Association Studies

The standard paradigm for the analysis of genome-wide association studies involves carrying out association tests at both typed and imputed SNPs. These methods will not be optimal for detecting the signal of association at SNPs that are not currently known or in regions where allelic heterogeneity o...

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Bibliografski detalji
Glavni autori: Su, Z, Cardin, N, Consortium, TWTCC, Donnelly, P, Marchini, J
Format: Journal article
Jezik:English
Izdano: 2010