STAT3-mediated astrocyte reactivity associated with brain metastasis contributes to neurovascular dysfunction
Astrocytes are thought to play a pivotal role in coupling neural activity and cerebral blood flow. However, it has been shown that astrocytes undergo morphological changes in response to brain metastasis, switching to a reactive phenotype which has the potential to significantly compromise cerebrova...
Main Authors: | Sarmiento Soto, M, Larkin, JR, Martin, C, Khrapitchev, AA, Maczka, M, Economopoulos, V, Scott, H, Escartin, C, Bonvento, G, Serres, S, Sibson, NR |
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Format: | Journal article |
Language: | English |
Published: |
American Association for Cancer Research
2020
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