Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1.
BACKGROUND AND PURPOSE: It is thought that the anti-inflammatory effects of glucocorticoids (GCs) are largely due to GC receptor (GR)-mediated transrepression of NF-κB and other transcription factors, whereas side effects are caused by activation of gene expression (transactivation). Selective GR m...
المؤلفون الرئيسيون: | Joanny, E, Ding, Q, Gong, L, Kong, P, Saklatvala, J, Clark, A |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2012
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مواد مشابهة
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Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1.
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Dual specificity phosphatase-1 (DUSP-1) - A novel mediator of the anti-inflammatory effects of glucocorticoids?
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Role of Dual-Specificity Phosphatase 1 in Glucocorticoid-Driven Anti-inflammatory Responses
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Glucocorticoid regulation of mouse and human dual specificity phosphatase 1 (DUSP1) genes: unusual cis-acting elements and unexpected evolutionary divergence.
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Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1.
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