Strong cation exchange (SCX) based analytical methods for the targeted analysis of protein post-translational modifications.

The multidimensional combination of strong cation exchange (SCX) chromatography and reversed phase chromatography has emerged as a powerful approach to separate peptides originating from complex samples such as digested cellular lysates or tissues before analysis by mass spectrometry, enabling the i...

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Bibliographic Details
Main Authors: Mohammed, S, Heck, A
Format: Journal article
Language:English
Published: 2011