Strong cation exchange (SCX) based analytical methods for the targeted analysis of protein post-translational modifications.
The multidimensional combination of strong cation exchange (SCX) chromatography and reversed phase chromatography has emerged as a powerful approach to separate peptides originating from complex samples such as digested cellular lysates or tissues before analysis by mass spectrometry, enabling the i...
المؤلفون الرئيسيون: | Mohammed, S, Heck, A |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2011
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مواد مشابهة
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Strong cation exchange-based fractionation of Lys-N-generated peptides facilitates the targeted analysis of post-translational modifications.
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Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex.
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Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
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