Restricted diffusion of a freely diffusible second messenger: Mechanisms underlying compartmentalized cAMP signalling

It is becoming increasingly evident that the freely diffusible second messenger cAMP can transduce specific responses by localized signalling. The machinery that underpins compartmentalized cAMP signalling is only now becoming appreciated. Adenylate cyclases, the enzymes that synthesize cAMP, are lo...

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Bibliographic Details
Main Authors: Zaccolo, M, Di Benedetto, G, Lissandron, V, Mancuso, L, Terrin, A, Zamparo, I
Format: Journal article
Published: 2006