A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes

Much of the virulence of Plasmodium falciparum malaria is caused by cytoadherence of infected erythrocytes, which promotes parasite survival by preventing clearance in the spleen. Adherence is mediated by membrane protrusions known as knobs, whose formation depends on the parasite-derived, knob-asso...

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Bibliographic Details
Main Authors: Watermeyer, J, Hale, V, Hackett, F, Clare, D, Cutts, E, Vakonakis, I, Fleck, R, Blackman, M, Saibil, H
Format: Journal article
Published: American Society of Hematology 2016