Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.

The U1 small nuclear (sn)RNA (U1) is a multifunctional ncRNA, known for its pivotal role in pre-mRNA splicing and regulation of RNA 3' end processing events. We recently demonstrated that a new class of human U1-like snRNAs, the variant (v)U1 snRNAs (vU1s), also participate in pre-mRNA processi...

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Bibliographic Details
Main Authors: Vazquez-Arango, P, Vowles, J, Browne, C, Hartfield, E, Fernandes, H, Mandefro, B, Sareen, D, James, W, Wade-Martins, R, Cowley, S, Murphy, S, O'Reilly, D
Format: Journal article
Language:English
Published: Oxford University Press 2016