Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNF-alpha: role of the p38 and p42/44 mitogen-activated protein kinases.

IL-10 is an anti-inflammatory cytokine with potent immunomodulatory effects, including inhibition of cytokine production. However, regulation of monocyte IL-10 production is poorly understood. In this report we have investigated the mechanisms of LPS-induced IL-10 production by human peripheral bloo...

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Hlavní autoři: Foey, A, Parry, S, Williams, L, Feldmann, M, Foxwell, B, Brennan, F
Médium: Journal article
Jazyk:English
Vydáno: 1998