The natural history of multiple sclerosis: a geographically based study. 4. Applications to planning and interpretation of clinical therapeutic trials.

The natural history of multiple sclerosis: a geographically based study. 4. Applications to planning and interpretation of clinical therapeutic trials.

We used hypothetical entry criteria typical of those used in clinical therapeutic trials to determine the patients who would have been eligible among those followed in a clinic-based study of multiple sclerosis (MS) in London, Ontario, between 1972 and 1984. For these patients, we determined the obs...

Bibliografski detalji
Glavni autori:	Weinshenker, BG, Rice, G, Noseworthy, J, Carriere, W, Baskerville, J, Ebers, G
Format:	Journal article
Jezik:	English
Izdano:	1991

Slični predmeti

The natural history of multiple sclerosis: a geographically based study. 3. Multivariate analysis of predictive factors and models of outcome.
od: Weinshenker, BG, i dr.
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The natural history of multiple sclerosis: a geographically based study. I. Clinical course and disability.
od: Weinshenker, BG, i dr.
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THE NATURAL-HISTORY OF MULTIPLE-SCLEROSIS - A GEOGRAPHICALLY BASED STUDY
od: Weinshenker, B, i dr.
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The natural history of multiple sclerosis: a geographically based study. 2. Predictive value of the early clinical course.
od: Weinshenker, BG, i dr.
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APPLICATIONS OF STUDIES OF THE NATURAL-HISTORY OF MULTIPLE-SCLEROSIS TO THE PLANNING AND INTERPRETATION OF CLINICAL-TRIALS
od: Weinshenker, B, i dr.
Izdano: (1989)

The natural history of multiple sclerosis: a geographically based study. 6. Applications to planning and interpretation of clinical therapeutic trials in primary progressive multiple sclerosis.
od: Cottrell, D, i dr.
Izdano: (1999)

The natural history of multiple sclerosis.
od: Weinshenker, BG, i dr.
Izdano: (1987)

A comparison of sporadic and familial multiple sclerosis.
od: Weinshenker, BG, i dr.
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The influence of pregnancy on disability from multiple sclerosis: a population-based study in Middlesex County, Ontario.
od: Weinshenker, BG, i dr.
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The natural history of multiple sclerosis: a geographically based study. 5. The clinical features and natural history of primary progressive multiple sclerosis.
od: Cottrell, D, i dr.
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The natural history of multiple sclerosis: a geographically based study 9: observations on the progressive phase of the disease
od: Kremenchutzky, M, i dr.
Izdano: (2006)

The natural history of multiple sclerosis: a geographically based study 9: observations on the progressive phase of the disease.
od: Kremenchutzky, M, i dr.
Izdano: (2006)

The natural history of multiple sclerosis: a geographically based study: 8: familial multiple sclerosis.
od: Ebers, G, i dr.
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IDENTIFYING SUITABLE CANDIDATES FOR CLINICAL-TRIALS OF PROGRESSIVE MULTIPLE-SCLEROSIS
od: Weinshenker, B, i dr.
Izdano: (1993)

The natural history of multiple sclerosis: a geographically based study. 7. Progressive-relapsing and relapsing-progressive multiple sclerosis: a re-evaluation.
od: Kremenchutzky, M, i dr.
Izdano: (1999)

The natural history of multiple sclerosis: a geographically based study 7. Progressive-relapsing and relapsing-progressive multiple sclerosis: a re-evaluation
od: Kremenchutzky, M, i dr.
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Systemic interferon alfa in multiple sclerosis.
od: Weinshenker, BG, i dr.
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Therapeutic trials in multiple sclerosis.
od: Noseworthy, J, i dr.
Izdano: (1984)

An open trial of OKT3 in patients with multiple sclerosis.
od: Weinshenker, BG, i dr.
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The prevalence of primary Sjogren's syndrome in a multiple sclerosis population.
od: Noseworthy, J, i dr.
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Some clinical and pathologic observations on chronic myelopathy: a variant of multiple sclerosis.
od: Weinshenker, BG, i dr.
Izdano: (1990)

TIZANIDINE VERSUS BACLOFEN IN THE TREATMENT OF SPASTICITY IN PATIENTS WITH MULTIPLE-SCLEROSIS - A DOUBLE-BLIND-STUDY
od: Bass, B, i dr.
Izdano: (1987)

Natural history of multiple sclerosis: Implications for interpretation of relapse suppression
od: Ebers, G
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SJOGRENS-SYNDROME MIMICKING MULTIPLE-SCLEROSIS - REPLY
od: Noseworthy, J, i dr.
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A double-blind, randomized, crossover trial of pemoline in fatigue associated with multiple sclerosis.
od: Weinshenker, BG, i dr.
Izdano: (1992)

Tizanidine versus baclofen in the treatment of spasticity in patients with multiple sclerosis.
od: Bass, B, i dr.
Izdano: (1988)

FAILURE TO FIND PATIENTS WITH NERVOUS-SYSTEM MANIFESTATIONS OF PRIMARY SJOGRENS SYNDROME IN A MULTIPLE-SCLEROSIS CLINIC POPULATION
od: Noseworthy, J, i dr.
Izdano: (1988)

Interpretation of single band patterns in CSF protein electrophoresis.
od: Bass, B, i dr.
Izdano: (1988)

The natural history of multiple sclerosis.
od: Ebers, G
Izdano: (2000)

Natural history of multiple sclerosis.
od: Ebers, G
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Natural history of multiple sclerosis
od: Ebers, G
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Primary biliary cirrhosis and multiple sclerosis.
od: Noseworthy, J, i dr.
Izdano: (1989)

The natural history of multiple sclerosis: Observations on the progressive phase of the disease
od: Ebers, G, i dr.
Izdano: (2005)

Neuroimaging in multiple sclerosis.
od: Noseworthy, J, i dr.
Izdano: (1984)

A study of the causes of death in multiple sclerosis (MS) patients
od: Kremenchutzky, M, i dr.
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The natural history of multiple sclerosis: a geographically based study 10: relapses and long-term disability.
od: Scalfari, A, i dr.
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A comparison of simulated short-term outcomes from multiple sclerosis natural history (NH) data and observed outcomes in a clinical trial (CT)
od: Kremenchutzky, M, i dr.
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A PRELIMINARY CLINICAL-TRIAL OF ORTHOCLONE OKT-STAR-3 TREATMENT IN CHRONICALLY PROGRESSIVE MULTIPLE-SCLEROSIS
od: Weinshenker, B, i dr.
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Natural history of primary progressive multiple sclerosis.
od: Ebers, G
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Chapter 3 Natural History of Multiple Sclerosis
od: Ebers, G
Izdano: (2003)