Tertiary amine synthesis via reductive coupling of amides with Grignard reagents
A new iridium catalyzed reductive coupling reaction of Grignard reagents and tertiary amides affording functionalised tertiary amine products via an efficient and technically-simple one-pot, two-stage experimental protocol, is reported. The reaction - which can be carried out on gram-scale using as...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
Royal Society
2017
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