Tertiary amine synthesis via reductive coupling of amides with Grignard reagents

A new iridium catalyzed reductive coupling reaction of Grignard reagents and tertiary amides affording functionalised tertiary amine products via an efficient and technically-simple one-pot, two-stage experimental protocol, is reported. The reaction - which can be carried out on gram-scale using as...

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Bibliografische gegevens
Hoofdauteurs: Xie, L, Dixon, D
Formaat: Journal article
Taal:English
Gepubliceerd in: Royal Society 2017