Tertiary amine synthesis via reductive coupling of amides with Grignard reagents

A new iridium catalyzed reductive coupling reaction of Grignard reagents and tertiary amides affording functionalised tertiary amine products via an efficient and technically-simple one-pot, two-stage experimental protocol, is reported. The reaction - which can be carried out on gram-scale using as...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Xie, L, Dixon, D
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Royal Society 2017