Signalling hypoxia by HIF hydroxylases.

Signalling hypoxia by HIF hydroxylases.

Analysis of oxygen sensitive pathways that regulate the hypoxia inducible factor (HIF) transcriptional system has revealed a novel role for oxygenases in signalling hypoxia. The enzymes, which catalyse hydroxylation of specific prolyl and asparaginyl residues in the regulatory HIF-alpha subunits, be...

書誌詳細
主要な著者:	Schofield, C, Ratcliffe, P
フォーマット:	Journal article
言語:	English
出版事項:	2005

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