JAG1-NOTCH4 mechanosensing drives atherosclerosis

Endothelial cell (EC) sensing of disturbed blood flow triggers atherosclerosis, a disease of arteries that causes heart attack and stroke, through poorly defined mechanisms. The Notch pathway plays a central role in blood vessel growth and homeostasis, but its potential role in sensing of disturbed...

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Bibliographic Details
Main Authors:	Souilhol, C, Tardajos Ayllon, B, Li, X, Diagbouga, MR, Zhou, Z, Canham, L, Roddie, H, Pirri, D, Chambers, EV, Dunning, MJ, Ariaans, M, Li, J, Fang, Y, Jørgensen, HF, Simons, M, Krams, R, Waltenberger, J, Fragiadaki, M, Ridger, V, De Val, S, Francis, SE, Chico, TJA, Serbanovic-Canic, J, Evans, PC
Format:	Journal article
Language:	English
Published:	American Association for the Advancement of Science 2022

JAG1-NOTCH4 mechanosensing drives atherosclerosis

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