Inferring structural variant cancer cell fraction
We present SVclone, a computational method for inferring the cancer cell fraction of structural variant (SV) breakpoints from whole-genome sequencing data. SVclone accurately determines the variant allele frequencies of both SV breakends, then simultaneously estimates the cancer cell fraction and SV...
| Main Authors: | , , , , , , , , , , |
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| 其他作者: | |
| 格式: | Journal article |
| 语言: | English |
| 出版: |
Springer Nature
2020
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