Inferring structural variant cancer cell fraction

Inferring structural variant cancer cell fraction

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We present SVclone, a computational method for inferring the cancer cell fraction of structural variant (SV) breakpoints from whole-genome sequencing data. SVclone accurately determines the variant allele frequencies of both SV breakends, then simultaneously estimates the cancer cell fraction and SV...

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מידע ביבליוגרפי
Main Authors: Cmero, M, Yuan, K, Ong, CS, Schröder, J, PCAWG Evolution and Heterogeneity Working Group, Corcoran, NM, Papenfuss, T, Hovens, CM, Markowetz, F, Macintyre, G, PCAWG Consortium
מחברים אחרים: Yang, T-P
פורמט: Journal article
שפה:English
יצא לאור: Springer Nature 2020
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