Role of PDE2A in cAMP/PKA signaling compartmentalization

<p><b>Background and Aims :</b> cAMP/PKA signaling is compartmentalized within the cell, with tight spatial and temporal control of signal propagation underpinning specificity of response. The cAMP-degrading enzymes, phosphodiesterases (PDEs), are key regulators of this process. Th...

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Bibliographic Details
Main Author: de Oliveira Jones Ferrão Lobo, M
Other Authors: Zaccolo, M
Format: Thesis
Published: 2018