Synthesis of bicyclo[3.1.1]heptanes, meta-substituted arene isosteres, from [3.1.1]propellane
<p>The use of saturated small-ring bridged hydrocarbons as bioisosteres for aromatic rings has become a popular tactic in drug discovery. Perhaps the best known of such hydrocarbons is bicyclo[1.1.1]pentane, for which the angle between the exit vectors of the bridgehead substituents is identic...
| Հիմնական հեղինակներ: | , , , , |
|---|---|
| Ձևաչափ: | Journal article |
| Լեզու: | English |
| Հրապարակվել է: |
Springer Nature
2025
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