Novel therapeutic approaches targeting matrix metalloproteinases in cardiovascular disease.

Matrix metalloproteinases (MMPs), are proteinases that participate in extracellular matrix remodelling and degradation. Under normal physiological conditions, the activities of MMPs are regulated at the level of transcription, of activation of the pro-MMP precursor zymogens and of inhibition by endo...

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Bibliographic Details
Main Authors: Briasoulis, A, Tousoulis, D, Papageorgiou, N, Kampoli, A, Androulakis, E, Antoniades, C, Tsiamis, E, Latsios, G, Stefanadis, C
Format: Journal article
Language:English
Published: 2012