Sequential search leads to faster, more efficient fragment-based de novo protein structure prediction

<p>Motivation: Most current de novo structure prediction methods randomly sample protein conformations and thus require large amounts of computational resource. Here, we consider a sequential sampling strategy, building on ideas from recent experimental work which shows that many proteins fold...

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Bibliographic Details
Main Authors: de Oliveira, S, Law, E, Shi, J, Deane, C
Format: Journal article
Language:English
Published: Oxford University Press 2017