Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.

Rheumatoid arthritis (RA) is an immune-mediated inflammatory disease affecting the joints. A heterogeneous response to available therapies demonstrates the need to identify those patients likely to benefit from a particular therapy. Our objective was to identify genetic factors associated with respo...

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Bibliographic Details
Main Authors: Wang, J, Bansal, A, Martin, M, Germer, S, Benayed, R, Essioux, L, Lee, J, Begovich, A, Hemmings, A, Kenwright, A, Taylor, K, Upmanyu, R, Cutler, P, Harari, O, Marchini, J, Criswell, L, Platt, A
Format: Journal article
Language:English
Published: 2013