Investigation into the regulatory mechanism of BRCA2 stability

Investigation into the regulatory mechanism of BRCA2 stability

<p>Inherited mutations in the BRCA2 gene predispose individuals to the development of breast and ovarian cancers. The BRCA2 protein plays a fundamental role in the repair of DNA double strand breaks by homologous recombination (HR). BRCA2 mediates the recruitment of the RAD51 recombinase to DN...

書誌詳細
第一著者:	Gruber, C
その他の著者:	Esashi, F
フォーマット:	学位論文
言語:	English
出版事項:	2013
主題:	Medical Sciences Biology (medical sciences) Biochemistry DNA damage signalling

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