Investigation into the regulatory mechanism of BRCA2 stability
<p>Inherited mutations in the BRCA2 gene predispose individuals to the development of breast and ovarian cancers. The BRCA2 protein plays a fundamental role in the repair of DNA double strand breaks by homologous recombination (HR). BRCA2 mediates the recruitment of the RAD51 recombinase to DN...
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| フォーマット: | 学位論文 |
| 言語: | English |
| 出版事項: |
2013
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