Cellular target engagement and selectivity profiling of small molecules for mechanism-of-action studies
<p>A high-quality chemical probe should possess the qualities of being highly specific, potent, and selective against off-target interactions, in order to enable target validation. By contrast, low-quality compounds, which display properties of promiscuity, reactivity and instability can in tu...
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| Format: | Thesis |
| Language: | English |
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2019
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