The continuum model of selection in human tumors: general paradigm or niche product?
Berger and colleagues recently proposed a continuum model of how somatic mutations cause tumors to grow, thus supplementing the established binary models, such as oncogene activation and "two hits" at tumor suppressor loci. In the basic continuum model, decreases or increases in gene funct...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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