TPepRet: a deep learning model for characterizing T-cell receptors–antigen binding patterns

Motivation: T-cell receptors (TCRs) elicit and mediate the adaptive immune response by recognizing antigenic peptides, a process pivotal for cancer immunotherapy, vaccine design, and autoimmune disease management. Understanding the intricate binding patterns between TCRs and peptides is critical for...

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Bibliographic Details
Main Authors: Wang, M, Fan, W, Wu, T, Li, M
Format: Journal article
Language:English
Published: Oxford University Press 2025